Wednesday, October 21, 2009

which factors determine whether the body defense mechanism is inflammation or immunoresponse ?


Answers:
Inflammation is itself an immunoresponse. It is the first response of the immune system to infection or irritation.
immumeresponse results into inflammation. they both are not different phenomenons. 0ne is cause and other is effect.
Well Inflammation occurs when the body (or more specifically the innate immune system) deems whatever it is reacting against a threat. Inflammation is a response. Inflammation occurs becuase more and more leukoycytes are being recruited to the site of infection. With no inflammation the cells of the innate immune system has no way of knowing where to move to.The innate system consisting of cells such as neutrophils and macrophage etc move by chemotaxis in response to cytokines such as interluekin (i think 7). The swelling is due to the epithlial cells becoming "leaky" and allowing the leukocytes to pass between them and move toward the site of infection.Ok i may have rushed my answer a bit but i think you'll get the gist.

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